(Agency reports)

A medicine that is originally formulated to treat diabetes and related complications has been attributed with the value of addressing kidney failure and cutting dialysis procedures, Bloomberg reported on Tuesday.

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The Oracle Today reports that kidney failure is a death sentence in Nigeria with very few ultra-wealthy patients who could afford transplant overseas standing slim chances of returning to normal life.

According to Bloomberg reports, Ozempic used in treating diabetes and a sister drug Wegovy used for obesity, , are being tested for additional results in redeeming failing kidney.

An independent data monitoring committee recommended halting the study after an interim analysis showed the drug hit an efficacy goal, Novo said late on Tuesday. The Danish drugmaker will get full results of the study once the process of closing it is complete. That’s expected by the first half of 2024.

The impact of Ozempic and a sister drug for obesity, Wegovy, looks likely to stretch into fields far beyond obesity and diabetes. Another large study recently showed that Wegovy cut the risk of heart attacks and strokes. And Walmart Inc. said last week it’s seeing an impact on grocery demand from people taking the drugs and other appetite-suppressing medications.

Stopping the trial early points to a “somewhat faster effect than we had previously contemplated,” Citigroup Inc. analyst Veronika Dubajova wrote in a note. Kidney disease is one of the areas where drugs like Ozempic could help reduce the number of patients over time, she said.

Novo’s surprise results are the latest in a string of blows to Fresenius Medical, the largest dialysis provider in the $36 billion US market, as it tries to orchestrate a turnaround after its costs soared and dialysis patients died during the Covid-19 pandemic. Investors were already worried about the impact of the so-called GLP-1 drugs on its business prior to the kidney study, according to Citi.

Fresenius Medical shares are down by about a third since Novo announced its positive heart disease study in August. The company declined to comment on Novo’s kidney trial.

Bad Homburg, Germany-based Fresenius Medical is also in the midst of leadership churn after changing its chief executive officer twice in the past year. Shareholders recently approved a plan to change the company’s legal structure to give it more autonomy from long-time parent entity Fresenius SE.

While Fresenius SE is giving up control, it retains a powerful voice as the largest shareholder. Fresenius SE CEO Michael Sen has said he has no intention of selling the 32% stake as he believes in the growth potential of the kidney-dialysis company. Fresenius SE shares also declined as much as 13% on Wednesday — the most since 2018.

Any shrinking of the kidney disease patient population may be 15 years in the future, Oddo BHF analysts wrote in a note. They argued that the new drugs could actually benefit dialysis providers in the short term by helping to ensure that those who start the treatment are already more closely monitored by doctors and less likely to die in the initial months of treatment.

Ozempic and Wegovy, both known generically as semaglutide, are part of a class of drugs that mimic the GLP-1 hormone released after eating. They help patients feel full for longer and also slow the movement of food through the digestive tract. First developed for type 2 diabetes, they’ve now shown unprecedented effectiveness for weight loss, spurring a market that Jefferies Financial Group Inc. estimated could grow to as much as $150 billion.

Novo’s trial, called FLOW, started in 2019 and looked at the progression of kidney impairment in people with type 2 diabetes and chronic kidney disease, enrolling more than 3,500 people in 28 countries.